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ISOTT 2013, Hanover, NH, USA

2013-10-06 15:01

The 41st Annual Meeting of ISOTT was held at the Hanover Inn in Hanover, NH, USA on June 24-28, 2013. The meeting was organized by Hal Swartz and colleagues at the EPR Center at the Geisel School of Medicine, Dartmouth College.


The ISOTT meeting was organized to have two days of overlap (June 25-26) with the International Conference on Electron Paramagnetic Resonance (EPR) Spectroscopy. The combined sessions focused on oxygen and EPR with emphasis on clinical aspects of oxygen and methods related to its measurement.


There were more than 230 attendees with more than 180 presentations on a variety of topics. Indicating the increasingly important role of oximetry in clinical medicine, the conference also featured a full day of clinical focus with presentations of clinical relevance related to tissue oxygenation in cerebral, muscular, cardiovascular, and renal pathophysiology and treatment. The presentation format was planned to facilitate and promote discussions, with extensive discussion time allocated for oral presentations. 


The participants also enjoyed local hospitality and visits to the Dartmouth campus, including the Dartmouth-Hitchcock Medical Center and the EPR Center.


The scientific programs included 7 sessions of oral presentations of 30- and 15-min duration, as well as 3 separate sessions on “Introduction to Poster” presentations, which provided an opportunity for the poster presenters to give a 2-min oral presentation highlighting the research work included in the poster.


The meeting started off with a welcome reception in the Hanover Inn on the evening of June 22. The scientific sessions on Day 1 (June 23) focused on the clinical aspects of tissue oxygenation. The highlights of the presentations included optical topography-based neuroimaging for studying cognitive functions in infants (Elwell), hypoxia and brain oxygenation (LaManna), influence of PaCO2 on brain hemodynamics and oxygenation (U. Wolf) and several other presentations on cerebral and muscle oxygenation. The evening social event was at the Dartmouth outing club where participants enjoyed the ambience of Occum Pond and more musical entertainment.


Day 2 sessions started off with a memorial lecture for David Maguire (1945-2013) given by  Okunieff and Cicco. M. Wolf gave an update of the status of instrumental and methodological approaches to optical imaging. The rest of presentations included the use of NIRS and related techniques, probes, and applications to a wide variety of disease conditions. The evening social event included a dinner in the Montshire Museum of Science (a self-guided science museum located in Norwich, Vermont). 


Day 3 which was the first day of the ISOTT/EPR combined meeting started off with an overview of the accomplishments and challenges of clinical EPR by Swartz, followed by a number of presentations on in vivo EPR oximetry and oxygen imaging by Halpern, Gallez, and others. The afternoon session continued on the use of EPR oximetry for a variety of applications including cancer radiation therapy, stroke, and renal diseases. The evening social program included an outdoor BBQ, balloon ride, fireworks, and musical background at the Swartz/Flood home.


Day 4 continued the combined ISOTT/EPR sessions and was held at the Dartmouth-Hitchcock Medical Center to enhance participation by clinicians. The morning session started off with the measurement and use of oxygenation for treating myocardial infarction (Kuppusamy), chronic versus acute hypoxia in tumors (Vaupel), use of Cerenkov emission for tissue oximetry (Pogue), and clinical measurement of tumor oxygenation (Jarvis). The highlights of the afternoon sessions included presentations on the advanced in vivo EPR methodologies including EPR imaging and dynamic nuclear polarization (DNP)-based metabolic imaging in cancer (Krishna), development of DNP-MRI (Utsumi), multifunctional imaging (Khramtsov), pH imaging (Hirata), and redox imaging (Li), and others. The combined sessions on EPR and oxygen concluded with an informative lecture by  Severinghaus on the discovery of oxygen. Participants then had an opportunity to tour the new EPR Center building that opened in March, 2013.


The ISOTT conference ended with a banquet and award ceremony in the EPR Center. There were many outstanding candidates who applied for the ISOTT 2013 awards. The following were the recipients of 2013 awards: Melvin H. Knisely award: Malou Friederich-Persson (Sweden); Dietrich Lübbers award: Nannan Sun (China); Britton Chance award: Tharindi Hapuarachchi (UK); Duane Bruley travel awards: Allann Al-Armaghany (UK), Gemma Bale (UK), Alexander Caicedo-Dorado (Belgium), and Luke Dunne (UK).

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